Correction: Regulation of α-Transducin and α-Gustducin Expression by a High Protein Diet in the Pig Gastrointestinal Tract.
نویسندگان
چکیده
There is an error in the Funding section. The correct funding information is as follows: The present work was supported by National Institutes of Health (NIH) grants DK098447 and 41301 (C.S.), grants from the Italian Ministry of Education, University and Research (MIUR; PRIN2009; R. De G.), from ‘Fondazione Del Monte di Bologna e Ravenna’, Italy, and funds from the University of Bologna (R. De G. and P.C.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
منابع مشابه
Regulation of α-Transducin and α-Gustducin Expression by a High Protein Diet in the Pig Gastrointestinal Tract
BACKGROUND The expression of taste receptors (TASRs) and their signalling molecules in the gastrointestinal (GI) epithelial cells, including enteroendocrine cells (EECs), suggests they participate in chemosensing mechanisms influencing GI physiology via the release of endocrine messengers. TASRs mediate gustatory signalling by interacting with different transducers, including α-gustducin (Gαgus...
متن کاملPartial Rescue of Taste Responses of α-Gustducin Null Mice by Transgenic Expression of α-Transducin
The transduction of responses to bitter and sweet compounds utilizes guanine nucleotide binding proteins (G proteins) and their coupled receptors. α-Gustducin, a transducin-like G protein α-subunit, and rod α-transducin are expressed in taste receptor cells. α-Gustducin knockout mice have profoundly diminished behavioral and electrophysiological responses to many bitter and sweet compounds, alt...
متن کاملExpression and regulation of α-transducin in the pig gastrointestinal tract
Taste signalling molecules are found in the gastrointestinal (GI) tract suggesting that they participate to chemosensing. We tested whether fasting and refeeding affect the expression of the taste signalling molecule, α-transducin (Gαtran ), throughout the pig GI tract and the peptide content of Gαtran cells. The highest density of Gαtran -immunoreactive (IR) cells was in the pylorus, followed ...
متن کاملBitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying.
Ghrelin is a hunger hormone with gastroprokinetic properties but the factors controlling ghrelin secretion from the stomach are unknown. Bitter taste receptors (T2R) and the gustatory G proteins, α-gustducin (gust) and α-transducin, are expressed in the gut and are involved in the chemosensation of nutrients. This study aimed to investigate whether T2R-agonists affect (i) ghrelin release via α-...
متن کاملSensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein
BACKGROUND Ghrelin is an important regulator of energy--and glucose homeostasis. The octanoylation at Ser(3) is essential for ghrelin's biological effects but the mechanisms involved in the octanoylation are unknown. We investigated whether the gustatory G-protein, α-gustducin, and the free fatty acid receptors GPR40 and GPR120 are involved in the fatty acid sensing mechanisms of the ghrelin ce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- PloS one
دوره 11 3 شماره
صفحات -
تاریخ انتشار 2016